Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Nov 23;9:1020006. doi: 10.3389/fcvm.2022.1020006

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Gupta, Khanal, Bhavnani, Mathias, Lallo, Kiriakou, Ferrell and Raman.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

TSP-1 deletion increases LMOD-1 and calponin expression in aortic vessels of male MetS KKAy^+/– mice. Shown are representative western blots for TSP-1, LMOD-1 and calponin expression in aortic lysates derived from (A) male KKAy^+/–TSP-1^+/+ and KKAy^+/–TSP-1^–/– mice and (B) female KKAy^+/–TSP-1^+/+ and KKAy^+/–TSP-1^–/– mice. Shown are summary graphs for densitometric quantification of immunoblots for (C) TSP-1, (D) Calponin, and (E) LMOD-1 expression. n = 5–7 animals per genotype per sex. All results are expressed as mean ± SEM. *p < 0.05, ***p < 0.0005. Loading control = Ponceau S. Data shown illustrates protein expression normalized to Ponceau S. For representative immunoblots, lane images depict proteins loaded and detected on a single immunoblot (full blots shown in Supplementary Figures 3, 4); however, lanes were re-arranged to improve the clarity of presentation.