TABLE 3.
Effect of CDPDP on croton oil-induced ear edema in mice.
| Groups | Weight of left ear (mg) | Weight of right ear (mg) | Edema (∆ mg) | % Reduction of inflammation |
|---|---|---|---|---|
| a) | ||||
| Control (Saline) | 80.04 ± 1.4 | 80.0 ± 2.02 | – | – |
| Croton oil | 91.4 ± 1.10 | 97.50 ± 2.1 | 6.10 ± 0.74 | – |
| Ibuprofen | 86.7 ± 1.67 | 87.86 ± 2.01 | 1.16 ± 0.10 | 80.47 ± 4.98a |
| CDPDP (20 mg/kg) | 90.44 ± 1.7 | 92.73 ± 1.5 | 2.29 ± 0.20 | 61.99 ± 4.07c |
| CDPDP (40 mg/kg) | 84.34 ± 2.1 | 86.07 ± 1.8 | 1.73 ± 0.15 | 71.98 ± 7.78b |
| b) Effect of CDPDP on croton oil-induced anal edema in mice | ||||
| Groups | Anus size (mm) | Edema (mm) | % reduction of inflammation | |
| Control (Saline) | 33.82 ± 0.89 | – | – | |
| Croton oil | 45.92 ± 1.19 | 12.46 ± 0.7 | – | |
| Ibuprofen | 35.95 ± 1.02 | 2.09 ± 0.11 | 81.99 ± 6.19a | |
| CDPDP (20 mg/kg) | 39.02 ± 1.59 | 4.48 ± 0.20 | 62.74 ± 4.06c | |
| CDPDP (40 mg/kg) | 38.12 ± 1.38 | 3.49 ± 0.27 | 69.78 ± 4.88b | |
The data values displayed are the mean standard deviation ± (n = 6). The means in the column with distinct superscript (a-c) letters are substantially different (p < 0.05).