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. 2022 Dec 6;42(12):BSR20221165. doi: 10.1042/BSR20221165

Figure 5. CREB phosphorylation regulates granzyme C induction.

Figure 5

BMMCs from three wild-type or four CREB Ser133Ala mice were stimulated with 10 ng/ml IL-33 for 24 h or left unstimulated. The levels of intracellular granzyme C were then determined by flow cytometry. Representative histograms are shown in (A) and quantification of the geometric mean in (B). The graph shows the mean and standard deviation with individual mice shown by symbols. For comparisons to the IL-33 only condition, P<0.001 is indicated by *** (two-way ANOVA followed Sidak’s post hoc testing).