Skip to main content
. 2022 Nov 23;12:1046239. doi: 10.3389/fonc.2022.1046239
Tumor type Morphology/Behavior Grade
Non-invasive (papillary) urothelial carcinoma, low-grade 1
Non-invasive (papillary) urothelial carcinoma, high-grade 8130/2* 3
Non-invasive (papillary) urothelial carcinoma, grade unknown 9
Urothelial carcinoma (with histologic examination), but invasion cannot be assessed
  • Papillary term mentioned or papillary appearance (exophytic lesion)

8130/2**
  • Papillary term not mentioned or no information about appearance

8120/2 *** 1/3/9
  • The clinical impression is of invasive disease

8120/3**** 3
Urothelial carcinoma in situ (carcinoma in situ) 8120/2 3*****
Invasive carcinoma, not otherwise specified (NOS) (1) 8010/3 3*****
Invasive urothelial carcinoma 8120/3 3*****

(1) Although most carcinomas of urinary tract are urothelial, there are also other carcinomas such as squamous or adenocarcinoma. Therefore, if urothelial or transitional cell is not specified on the pathological report, code “8010/3”. But if non-invasive urothelial carcinoma was previously diagnosed, record (code) as urothelial carcinoma (8120/3), provided that prostate carcinoma invading the urinary bladder is ruled out. Also, if the concept urothelial is in the tumor description, code 8120/3 even if not specified in the final diagnosis.

(*) When the term “papillary” is not specified in the pathological report but the pathology report indicates an urothelial carcinoma with pTa stage, code 8130/2 (plus grade, if specified)

(**) In this case, code pTa.

(***) In this case the code pT is pTX (and not pTis), so as not to be confused with Carcinoma in situ.

(****) If the clinical impression is of invasive disease, then code with/3 behavior code and grade 3.

(*****) All in situ and invasive carcinomas must be recorded as high grade. Although the pathology report may indicate “low grade” or not indicate a grade, if it is an in situ or invasive tumor, it must be considered high grade.”