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. 2022 Nov 23;13:956907. doi: 10.3389/fimmu.2022.956907

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Copyright © 2022 Chitnis, Kaskow, Case, Hanus, Li, Varghese, Healy, Gauthier, Saraceno, Saxena, Lokhande, Moreira, Zurawski, Roditi, Bergmark, Giovannoni, Torti, Li, Quintana, Clementi, Shailubhai, Weiner and Baecher-Allan

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Serum IgG and IgM antibody reactivity in patients treated with 50ug. Heatmap representing the mean delta change from Timepoint 1(baseline) to Timepoint 2 (day 7) for: IgG (A) and IgM (B) antibody reactivity in serum samples from patients. (C) Volcano plot representing differential IgG and IgM antibody reactivity. Cut-off criteria was defined as p-value < 0.05 and log2 fold change > 1 or < −1.