Table 1.

Fatty acid unsaturation ratios in rat, rabbit, human, and OP9 cells from red and yellow BMAds.

Origin	BMAd type	16:1/16:0	c/r	18:1/18:0	c/r	Reference
Rat	constitutive regulated	0.25 0.09	2.8	1.18 0.81	1.5	Scheller et al., 2015
Rabbit	constitutive regulated	0.53 0.16	3.3	7.52 2.68	2.8	Tavassoli et al., 1977
Human	constitutive regulated	0.19 0.11	1.7	7.91 4.40	1.8	original data
OP9 cells	induced spontaneous	0.84 0.24	1.6	4.74 2.33	2.0	original data

The 16:1/16:0 and 18:1/18:0 unsaturation ratios were calculated from the proportion of total fatty acids. Rat BM data from Scheller et al., 2015 Supplementary Data 1 (regulated: femur and proximal tibia, constitutive: distal tibia). Rabbit BM data from Tavassoli 1977 Table 1 (regulated: vertebrae, constitutive: os calcis). Human original data from Figure 7 (regulated: iliac crest post-chemotherapy, constitutive: femoral head) and OP9 cell original data from Figure 6 (regulated: spontaneous, constitutive: induced) from HPLC analysis. Additional measurements in human BM have been made by MRI spectroscopy but cannot be compiled with these data due to the different methodology (37, 38). c, constitutive; r, regulated.