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. 2022 Nov 23;14:1020224. doi: 10.3389/fnagi.2022.1020224

Table 1.

The inclusive/exclusive criteria.

Inclusion criteria

  1. Aged 18–70 years*

  2. Nontraumatic spontaneous intracerebral hemorrhage*

  3. Patients with postoperative high risk of MACCPE*

    1. Previous history of cerebral infarction or TIA.

    2. Previous history of coronary heart disease or myocardial infarction.

    3. ASCVD Risk Estimator Plus: 10 years risk > 10%.

    4. The Caprini Risk Scale: Score > 2.

  4. Received neurosurgical procedures

  5. Signed informed consent.

  6. No history of allergy to salicylic acid preparation.*

  7. Complete the preintervention assessment and meet the fellow criteria:

    1. Postoperative head CT showed no new infarction or hemorrhage

    2. Postoperative venous ultrasound of the lower extremity did not reveal deep vein thrombosis

    3. Postoperative electrocardiogram and myocardial enzyme examination did not show acute myocardial ischemia or myocardial infarction.

Exclusion criteria

  1. Structural cerebrovascular lesions (such as intracranial aneurysms, cerebrovascular malformations, etc.) or tumors in the area of bleeding or the bleeding is suspected to be related to these lesions

  2. Ischemic stroke with hemorrhagic conversion

  3. Secondary bleeding due to venous embolism

  4. The malignant tumor is expected to have a survival of no more than 3 months.

  5. Take antithrombotic agents, such as Vitamin K antagonists (warfarin) or new anticoagulants (Dabigatun Rivaroxaban) in addition to antiplatelet agents.

  6. Previous history of thrombocytopenia or coagulation disorders.

  7. Previous history of atrial fibrillation.

  8. Antiplatelet-related intracerebral hemorrhage

  9. Cerebral amyloid angiopathy-related intracerebral hemorrhage

*

The inclusion criteria of primary screening.