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. 2022 Nov 23;12:969396. doi: 10.3389/fonc.2022.969396

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Copyright © 2022 García-Vargas, Roque-Reyes, Arroyo-Villegas, Santiago-Negron, Sánchez-Vázquez, Rivera-Torres, Reyes-Meléndez, Cardona-Berdecía, García-Maldonado, Víquez and Martínez-Ferrer

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BAT1 down-regulation increased PC3 prostate cancer cell migration and BAT1 overexpression decreased PC3 prostate cancer cell migration. (A) Representative images of Control PC3 and siBAT1 PC3 cells using 4X magnification. (B) Relative invasion of siBAT1 PC3 cells caused a significant increase in migration at 12hrs (**P < 0.01) and 24hrs (*P < 0.05) when compared to control. (C) Representative images of Control PC3 and BAT1cDNA PC3 cells using 4X magnification. (D) Relative invasion of (+) BAT1cDNA PC3 cells caused a significant decrease in migration at 12hrs (**P < 0.01) and 24hrs (***P < 0.001) when compared to control.