Figure 8.

VSP inhibited the protein level of UP III in the mouse bladder. (A), Representative co-stained images with UP III and DAPI captured the bladder tissue of the UPEC CFT073-infected C3H/HeN mice. Yellow rectangle: higher magnification view of the selected area (parallel sections, the green signals represent UP III, the blue signals represent DAPI, scale bar = 50 μm). (B), Representative scatterplots for UPIII expression from the bladder tissue of the C3H/HeN mice infected with UPEC CFT073. (C), Statistical analysis of the UPIII-positive cells in the entire cross-sectional tissue region of the mouse bladder. Quantitatively, the percentage of cells expressing UPIII (UPIIII/DAPI). n=3 mice per group, compared with the control group: ^## p < 0.01; compared with the model group: ^*p < 0.05. The results were determined by Wilcoxon rank-sum test.