TABLE 2.
Mean action potentials elicited (±s.e.m.) by twenty electrical stimuli at the basal time (t = 0) in the different experimental groups. Since the normality test failed (Shapiro-Wilk), a Kruskal-Wallis one-way ANOVA on ranks was performed to compare the action potential elicited by the different treatments.
| Control (n = 5) | Vehicle (n = 5) | Clonidine 1 nmol (n = 5) | Clonidine 10 nmol (n = 5) | Cloni (10) + BRL 44408 (n = 5) | JP 1301 1 nmol (n = 5) | JP 1301 10 nmol (n = 5) | ANOVA on ranks | |
|---|---|---|---|---|---|---|---|---|
| Total APs | 502.4 ± 80.5 | 724.6 ± 194.2 | 762.8 ± 143.4 | 634.2 ± 130.3 | 709.2 ± 209.1 | 617.8 ± 93.5 | 387.5 ± 92.0 | χ2 = 4.535 p = 0.605 |
| Aβ-fibers | 131.8 ± 8.5 | 123 ± 17.5 | 134.8 ± 14.7 | 120.6 ± 20.3 | 141 ± 26.8 | 122 ± 14.31 | 116.0 ± 26.9 | χ2 = 0.872 p = 0.990 |
| Aδ-fibers | 38.4 ± 10.6 | 60 ± 19.0 | 49.2 ± 14.5 | 65 ± 7.78 | 75.6 ± 22.3 | 70.2 ± 6.8 | 43.5 ± 10.2 | χ2 = 7.024 p = 0.319 |
| C-fibers | 226.4 ± 35.6 | 363.20 ± 115.0 | 361.2 ± 101.0 | 316.4 ± 83.4 | 342 ± 119.5 | 293.4 ± 65.2 | 175.6 ± 57.0 | χ2 = 1.1 p = 0.954 |
| Post-discharge | 105.8 ± 39.9 | 178.4 ± 60.4 | 127.60 ± 38.7 | 132.2 ± 40.6 | 150.6 ± 61.8 | 132.2 ± 33.9 | 42.3 ± 12.7 | χ2 = 5.809 p = 0.445 |