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. 2022 Nov 23;13:1063957. doi: 10.3389/fimmu.2022.1063957

Table 1.

Clinical characteristics of the HCs and KTRs.

Parameters HCs (n = 26) KTRs P value#
All KTRs (n = 115) Stable KTRs (n = 65) Infection KTRs (n = 50) P value*
Male recipient, n (%) 15 (57.7%) 70 (60.9%) 45 (69.2%) 25 (50.0%) 0.036 0.428
Age, yrs ± SD 31.31 ± 10.65 42.02 ± 12.16 44.55 ± 9.56 44.30 ± 13.05 0.112 < 0.001
Donor, n (%) NA 0.743 NA
DCD 83 (72.2%) 49 (69.2%) 34 (68.0%)
Relative 32 (27.8%) 16 (30.8%) 16 (32.0%)
Infection site, n (%) NA NA NA NA NA
Pneumonia 27 (54%)
Urinary infection 17 (34%)
Other infection 6 (12%)
Calcineurin inhibitor, n (%) NA 0.412 NA
Tacrolimus 108 (93.9%) 60 (92.3%) 48 (96.0%)
Cyclosporine A 7 (6.1%) 5 (7.7%) 2 (4.0%)
Time from transplant to 1st test, months ± SD NA 62.64± 52.90 69.86 ± 48.69 53.26 ± 57.06 0.295 NA
WBC (109/L) NA 7.29 ± 3.27 6.78 ± 2.10 7.94 ± 4.28 0.076 NA
Neu (109/L) NA 7.02 ± 10.83 6.48 ± 11.18 7.74 ± 10.43 0.537 NA
Lym (109/L) NA 1.32 ± 0.74 1.64 ± 0.69 0.90 ± 0.58 < 0.001 NA
Cr admission (μmol/L) NA 143.73 ± 88.42 121.91 ± 54.94 172.10 ± 113.10 < 0.001 NA

*Comparison between the stable KTRs and the infection KTRs.

#Comparison among the three groups.

HCs, healthy controls; KTRs, kidney transplant recipients; SD, standard deviation; DCD, donation after citizens’ death; WBC, white blood cell counts; Neu, neutrophils count; Lym, lymphocyte counts; Cr, serum creatinine; NA, not available.