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. 2022 Nov 23;12:1043177. doi: 10.3389/fonc.2022.1043177

Figure 2.

Figure 2

ZNF24 and SLC7A5 are up-regulated in lung adenocarcinoma cell lines and tissues with KRAS mutation. (A, B) qRT-PCR and Western blot analysis showed that ZNF24 and SLC7A5 were significantly up-regulated in lung adenocarcinoma cells with KRAS mutation. (C–F) Immunohistochemical staining of SLC7A5 and ZNF24 in tissue microarray showed that ZNF24 and SLC7A5 were significantly up-regulated in lung adenocarcinoma tissues with KRAS mutation. (G, H) qRT-PCR and Western blot analysis showed that ZNF24 and SLC7A5 were significantly upregulated in lung adenocarcinoma clinical tissue samples with KRAS mutation. The experiments were repeated 3 times. Data are shown as means ± SD. P values were calculated with two-tailed Student’s t-test, *p < 0.05, **p < 0.01, ***p < 0.001. ns, not significant.