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. 2022 Dec 8;11(6):e220189. doi: 10.1530/ETJ-22-0189

Table 2.

Characteristics of high-risk thyroid eye disease patients

Background
  •  Male sex

  •  Age >50 years

  •  Tobacco smoker

History
  •  Unstable thyroid function

  •  Diabetes mellitus

  •  Radioiodine in the past 6 months

  •  Progressive symptoms and/or signs of TED

  •  Orbital aching

  •  Diplopia

Examination
  •  Marked soft tissue inflammatory features

  •  Lagophthalmos (Fig. 2A)

  •  Impaired ocular motility, particularly elevation

The features outlined are associated with an increased probability of developing sight-threatening TED (24).