Table 3.
Association of CD44V6 and RCAS1 Expression with Clinicopathologic Variables of 52 Patients with Cervical Cancer
| Clinicopathologic variables | Total | CD44v6 | P value | RCAS1 | P value | ||
|---|---|---|---|---|---|---|---|
| Positive (%) | Negative (%) | Positive (%) | Negative (%) | ||||
| Histologic type | <0.001* | 0.001* | |||||
| SCC | 28 | 24 (80) | 4 (18) | 11 (35) | 17 (81) | ||
| Adenocarcinoma | 24 | 6 (20) | 18 (82) | 20 (65) | 4 (19) | ||
| Age (years) | 0.7 | 0.5 | |||||
| <45 | 23 | 14 (47) | 9 (41) | 15 (48) | 8 (38) | ||
| ≥45 | 29 | 16 (53) | 13 (59) | 16 (52) | 13 (62) | ||
| Histologic grade | <0.001* | 0.057 | |||||
| G1 | 20 | 4 (13) | 16 (73) | 16 (52) | 4 (19) | ||
| G2 | 16 | 16 (53) | 0 (0) | 7 (23) | 9 (43) | ||
| G3 | 16 | 10 (33) | 6 (27) | 8 (26) | 8 (38) | ||
| FIGO stage | 0.3 | 0.3 | |||||
| I | 48 | 29 (97) | 19 (86) | 30 (97) | 18 (86) | ||
| II | 4 | 1 (3.3) | 3 (14) | 1 (3.2) | 3 (14) | ||
| Tumor size (mm) | 0.030* | 0.9 | |||||
| <25 | 24 | 10 (33) | 14 (64) | 14 (45) | 10 (48) | ||
| ≥25 | 28 | 20 (67) | 8 (36) | 17 (55) | 11 (52) | ||
| LVSI | 0.13 | 0.6 | |||||
| Negative | 22 | 10 (33) | 12 (55) | 14 (45) | 8 (38) | ||
| Positive | 30 | 20 (67) | 10 (45) | 17 (55) | 13 (62) | ||
| Pelvic lymph node metastasis | 0.4 | 0.9 | |||||
| Negative | 43 | 24 (83) | 19 (95) | 25 (89) | 18 (86) | ||
| Positive | 6 | 5 (17) | 1 (5) | 3 (11) | 3 (14) | ||
| None | 3 | 1 | 2 | 3 | 0 | ||
| Recurrence | 0.144 | 0.708 | |||||
| Negative | 43 | 27 (90) | 16 (73) | 28 (85) | 15 (79) | ||
| Positive | 9 | 3 (10) | 6 (27) | 5 (15) | 4 (21) | ||
LVSI, Lymph-vascular space invasion; *P<0.05