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IC50 Values of the Etoposide Alone and in Combination with siRNAs in Leukemia Cells
| Treatment | IC50 |
|---|---|
| Etoposide | 16.06 ± 1.08 |
| Etoposide + NC siRNA | 15.12 ± 0.33 |
| Etoposide + Mcl-1 siRNA | 10.41 ± 1.08* |
| Etoposide + Survivin siRNA | 9.23 ± 0.33* |
| Etoposide + Mcl-1 siRNA + Survivin siRNA | 7.08 ± 1.08# |
IC50 was calculated using sigmoidal dose-response model and Prism software. Data are expressed as the mean±SD (n=3). *p<0.05 versus etoposide; #p<0.05 versus single transfection.
