Skip to main content
. 2022 Jul;23(7):2341–2350. doi: 10.31557/APJCP.2022.23.7.2341

Table 2.

Top 10 GO Terms Ranked by p-value and DEG Count

ID Term Count p-value
Biological Process
GO:0008152 Metabolic process 10 1.27E-04
GO:0000165 MAPK cascade 11 8.20E-04
GO:0098609 Cell-cell adhesion 10 0.003782
GO:0007155 Cell adhesion 13 0.006135
GO:0043547 Positive regulation of GTPase activity 14 0.012209
GO:0000122 Negative regulation of transcription from RNA polymerase II promoter 16 0.016964
GO:0045893 Positive regulation of transcription, DNA-templated 12 0.032698
GO:0006468 protein phosphorylation 11 0.034977
GO:0007165 Signal transduction 21 0.039678
GO:0007399 Nervous system development 8 0.044982
Cellular Component
GO:0070062 Extracellular exosome 56 5.82E-06
GO:0005737 Cytoplasm 83 7.53E-05
GO:0005829 Cytosol 56 5.61E-04
GO:0005654 Nucleoplasm 49 6.08E-04
GO:0016020 Membrane 41 6.99E-04
GO:0005783 Endoplasmic reticulum 19 0.004083
GO:0005789 Endoplasmic reticulum membrane 19 0.006149
GO:0005634 Nucleus 74 0.017642
GO:0005730 Nucleolus 17 0.024886
GO:0005615 Extracellular space 23 0.03608
Molecular Function
GO:0005515 protein binding 125 1.57E-05
GO:0044822 poly(A) RNA binding 27 2.35E-04
GO:0019899 enzyme binding 13 3.01E-04
GO:0098641 cadherin binding involved in cell-cell adhesion 10 0.004606
GO:0004672 protein kinase activity 11 0.00611
GO:0004674 protein serine/threonine kinase activity 11 0.008358
GO:0042803 protein homodimerization activity 16 0.013938
GO:0016301 kinase activity 8 0.016625
GO:0003713 transcription coactivator activity 8 0.019217
GO:0005524 ATP binding 25 0.035337