Table 2.
Top 10 GO Terms Ranked by p-value and DEG Count
| ID | Term | Count | p-value |
|---|---|---|---|
| Biological Process | |||
| GO:0008152 | Metabolic process | 10 | 1.27E-04 |
| GO:0000165 | MAPK cascade | 11 | 8.20E-04 |
| GO:0098609 | Cell-cell adhesion | 10 | 0.003782 |
| GO:0007155 | Cell adhesion | 13 | 0.006135 |
| GO:0043547 | Positive regulation of GTPase activity | 14 | 0.012209 |
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | 16 | 0.016964 |
| GO:0045893 | Positive regulation of transcription, DNA-templated | 12 | 0.032698 |
| GO:0006468 | protein phosphorylation | 11 | 0.034977 |
| GO:0007165 | Signal transduction | 21 | 0.039678 |
| GO:0007399 | Nervous system development | 8 | 0.044982 |
| Cellular Component | |||
| GO:0070062 | Extracellular exosome | 56 | 5.82E-06 |
| GO:0005737 | Cytoplasm | 83 | 7.53E-05 |
| GO:0005829 | Cytosol | 56 | 5.61E-04 |
| GO:0005654 | Nucleoplasm | 49 | 6.08E-04 |
| GO:0016020 | Membrane | 41 | 6.99E-04 |
| GO:0005783 | Endoplasmic reticulum | 19 | 0.004083 |
| GO:0005789 | Endoplasmic reticulum membrane | 19 | 0.006149 |
| GO:0005634 | Nucleus | 74 | 0.017642 |
| GO:0005730 | Nucleolus | 17 | 0.024886 |
| GO:0005615 | Extracellular space | 23 | 0.03608 |
| Molecular Function | |||
| GO:0005515 | protein binding | 125 | 1.57E-05 |
| GO:0044822 | poly(A) RNA binding | 27 | 2.35E-04 |
| GO:0019899 | enzyme binding | 13 | 3.01E-04 |
| GO:0098641 | cadherin binding involved in cell-cell adhesion | 10 | 0.004606 |
| GO:0004672 | protein kinase activity | 11 | 0.00611 |
| GO:0004674 | protein serine/threonine kinase activity | 11 | 0.008358 |
| GO:0042803 | protein homodimerization activity | 16 | 0.013938 |
| GO:0016301 | kinase activity | 8 | 0.016625 |
| GO:0003713 | transcription coactivator activity | 8 | 0.019217 |
| GO:0005524 | ATP binding | 25 | 0.035337 |