Table 1.

Pathological Profile and Protein Expression (ER, PR, HER2, TP53, Ki67, CK5/6 and CK8/18) in EBV Positive (EBER1) Cases (n= 5)

In situ hibridization			Immunohistochemistry												Histopathology
			ER		PR		HER2		TP53		Ki67		CK5/6	CK8/18
Age	R	S	R	LI	R	LI	R	E	R	LI	R	LI	R	R	G	S. Tumor
55	+	F	+	60	+	20	-	-	-	0	+	99	-	+	III	T2
45	+	F	+	5	-	0	-	-	+	80	+	8	-	+	I	T2
64	+	F	+	40	-	0	-	+	-	0	+	35	-	+	I	T1
54	+	F	+	80	+	40	-	+	-	0	+	20	-	+	III	T1
47	+	F	+	80	+	80	+	+++	+	95	+	25	-	+	III	T3

ER, estrogen receptor; PR, progesterone receptor; HER2, epidermal growth factor receptor 2; CK, cytokeratin; R, result; S, staining; F, focal;

LI, labelling index (%); E, score; G, grade; S, tumor: tumor size.