Table 3.
Association of lp(a) levels with risk of renal function damage stratified by hypertension.
| Hypertension | Normotension | |||||
|---|---|---|---|---|---|---|
| Cases, N (%) | OR (95%CI) | P | Cases, N (%) | OR (95%CI) | P | |
| Continuous | ||||||
| lp (a) | 4012 (15.8) | 1.004 (1.001, 1.007) | 0.011 | 1.006 (1.004, 1.009) | <0.001 | |
| Categorical | ||||||
| <25% | 420 (21.8) | Ref. | – | 356 (8.1) | Ref. | – |
| 25 to <50% | 432 (25.2) | 1.107 (0.931, 1.318) | 0.250 | 538 (11.6) | 1.394 (1.195, 1.625) | <0.001 |
| 50 to <75% | 526 (31.2) | 1.407 (1.186, 1.670) | <0.001 | 567 (12.2) | 1.499 (1.284, 1.750) | <0.001 |
| 75 to <90% | 314 (31.3) | 1.307 (1.072, 1.594) | 0.008 | 374 (13.4) | 1.608 (1.354, 1.750) | <0.001 |
| 90 to <95% | 93 (29.6) | 1.166 (0.862, 1.578) | 0.319 | 133 (13.9) | 1.771 (1.395, 2.249) | <0.001 |
| ≥95% | 117 (35.0) | 1.458 (1.087, 1.955) | 0.012 | 142 (15.2) | 1.809 (1.430, 2.289) | <0.001 |
| P for trend | 0.001 | <0.001 | ||||
Adjusted for adjusted for age, gender, region, BMI, HDL-C, LDL-C, TG, TC, current smoking status, alcohol taking, exercise, education status, diabetes mellitus, BUN, UA, CRPHS.