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. 2022 Nov 23;9:1003233. doi: 10.3389/fcvm.2022.1003233

Table 5.

The temporal trends of ASIR, ASPR, ASDR, and ASDALYR from 1990 to 2019 of CAVD.

EAPC of ASIR No. (95% CI) EAPC of ASPR No. (95% CI) EAPC of ASDR No. (95% CI) EAPC of ASDALYR No. (95% CI)
Male Female Both Male Female Both Male Female Both Male Female Both
Global 3.04 (2.87~3.21) 3.06 (2.75~3.38) 3.03 (2.8~3.27) 3.67 (3.46~3.88) 3.62 (3.31~3.93) 3.65 (3.4~3.91) 0.05 (−0.06~0.16) 0.09 (−0.03~0.21) 0.06 (−0.04~0.15) −0.5 (−0.61~−0.39) −0.37 (−0.44~−0.3) −0.45 (−0.52~−0.38)
SDI level
High SDI 2.71 (2.45~2.98) 3.15 (2.81~3.49) 2.93 (2.62~3.23) 2.78 (2.54~3.01) 3.26 (2.96~3.57) 3.05 (2.78~3.32) −0.34 (−0.53~−0.16) 0 (−0.1~0.1) −0.14 (−0.27~−0.02) −1.09 (−1.32~−0.87) −0.6 (−0.71~−0.48) −0.84 (−1.01~−0.67)
High–middle SDI 4.94 (4.83~5.04) 5.31 (4.98~5.65) 5.1 (4.92~5.27) 5.8 (5.63~5.98) 6.49 (6.12~6.87) 6.11 (5.87~6.35) 0.96 (0.75~1.17) 1.38 (1.06~1.71) 1.17 (0.89~1.45) 0.29 (0.17~0.4) 0.79 (0.59~0.99) 0.51 (0.36~0.67)
Middle SDI 3.56 (3.14~3.98) 4.57 (4.11~5.03) 3.92 (3.5~4.35) 7.65 (7.36~7.95) 9.3 (8.95~9.64) 8.19 (7.9~8.49) 0.06 (−0.01~0.13) 0 (−0.08~0.08) 0.01 (−0.06~0.08) −0.12 (−0.19~−0.04) −0.2 (−0.28~−0.11) −0.17 (−0.24~−0.1)
Low–middle SDI 0.75 (0.64~0.87) 1.22 (1.04~1.4) 0.83 (0.69~0.97) 3.64 (3.46~3.82) 4.94 (4.7~5.18) 3.97 (3.76~4.17) 0.16 (0.09~0.24) 0.22 (0.13~0.31) 0.16 (0.08~0.24) 0.09 (0.04~0.15) 0.13 (0.04~0.23) 0.08 (0.01~0.14)
Low SDI 0 (−0.04~0.04) 0.49 (0.41~0.56) 0.12 (0.07~0.17) 1.47 (1.4~1.54) 1.85 (1.78~1.92) 1.51 (1.45~1.57) 0.01 (−0.02~0.05) 0.17 (0.09~0.25) 0.07 (0.01~0.12) −0.19 (−0.23~−0.15) −0.03 (−0.13~0.07) −0.15 (−0.21~−0.09)
World Bank Income Level
World Bank High Income 3.03 (2.73~3.32) 3.56 (3.18~3.95) 3.28 (2.94~3.63) 3.13 (2.84~3.43) 3.73 (3.37~4.08) 3.45 (3.13~3.78) −0.06 (−0.21~0.08) 0.27 (0.17~0.36) 0.12 (0.02~0.22) −0.81 (−0.98~−0.64) −0.31 (−0.4~−0.22) −0.56 (−0.68~−0.44)
World Bank Upper Middle Income 5.14 (4.76~5.51) 5.03 (4.73~5.34) 5.1 (4.76~5.44) 6.93 (6.65~7.22) 7.5 (7.2~7.79) 7.13 (6.86~7.4) 0.03 (−0.04~0.1) 0.15 (0.1~0.2) 0.07 (0.01~0.12) −0.08 (−0.16~0) 0.05 (−0.03~0.12) −0.04 (−0.11~0.03)
World Bank Lower Middle Income 1.24 (1.05~1.42) 1.47 (1.24~1.7) 1.28 (1.08~1.47) 3.42 (2.97~3.86) 2.87 (2.37~3.38) 3.24 (2.8~3.69) 0.15 (0.08~0.21) 0.36 (0.25~0.46) 0.23 (0.15~0.31) 0.07 (0.02~0.12) 0.18 (0.09~0.27) 0.1 (0.03~0.16)
World Bank Low Income 0.06 (0.04~0.08) 0.42 (0.38~0.45) 0.17 (0.14~0.21) 1.81 (1.72~1.89) 2.3 (2.13~2.48) 1.95 (1.83~2.06) −0.01 (−0.05~0.03) −0.07 (−0.14~0) −0.05 (−0.11~0) −0.24 (−0.3~−0.19) −0.35 (−0.46~−0.24) −0.29 (−0.37~−0.21)
Region
Andean Latin America 5.97 (5.43~6.52) 3.72 (3.24~4.19) 5.3 (4.78~5.82) 9.3 (8.14~10.48) 7.35 (6.26~8.45) 8.76 (7.62~9.91) −0.03 (−0.14~0.08) −0.76 (−0.94~−0.58) −0.34 (−0.46~−0.22) −0.03 (−0.14~0.07) −0.82 (−1~−0.65) −0.35 (−0.47~−0.23)
Australasia 7.65 (7.33~7.96) 7.86 (7.69~8.04) 7.72 (7.51~7.94) 10.25 (9.63~10.88) 10.22 (9.84~10.6) 10.18 (9.7~10.67) −0.59 (−0.84~−0.34) −0.43 (−0.63~−0.23) −0.49 (−0.71~−0.27) −0.99 (−1.3~−0.68) −0.45 (−0.72~−0.18) −0.75 (−1.04~−0.45)
Caribbean 3.87 (3.74~3.99) 3.27 (3.1~3.43) 3.75 (3.63~3.87) 7.36 (7.01~7.71) 6.94 (6.43~7.45) 7.25 (6.88~7.61) −0.08 (−0.29~0.13) 0.53 (0.33~0.72) 0.12 (−0.09~0.32) −0.2 (−0.43~0.04) 0.42 (0.26~0.58) −0.01 (−0.22~0.19)
Central Asia 5.5 (5.12~5.88) 4.43 (3.58~5.28) 5.26 (4.72~5.8) 7.59 (7.17~8.02) 5.57 (4.58~6.57) 6.92 (6.29~7.55) 2.81 (2.54~3.08) 4.54 (3.99~5.09) 3.72 (3.32~4.12) 2.64 (2.4~2.88) 3.57 (3.19~3.95) 3.08 (2.79~3.36)
Central Europe 6.03 (5.8~6.26) 6.87 (6.64~7.09) 6.43 (6.21~6.66) 6.47 (6.26~6.69) 7.35 (7.14~7.56) 6.92 (6.71~7.12) 4.06 (3.7~4.43) 5.6 (5.13~6.08) 4.85 (4.43~5.27) 3.41 (3.07~3.74) 4.81 (4.44~5.17) 4.02 (3.68~4.36)
Central Latin America 3.49 (3.16~3.81) 3.6 (3.19~4.02) 3.5 (3.16~3.83) 5.89 (5.39~6.4) 6.97 (6.11~7.83) 6.17 (5.57~6.78) 0.01 (−0.25~0.28) 0.53 (0.27~0.78) 0.2 (−0.06~0.46) −0.22 (−0.49~0.05) 0.34 (0.07~0.6) −0.04 (−0.31~0.23)
Central Sub–Saharan Africa 0.01 (−0.07~0.09) 0.26 (0.18~0.35) 0.12 (0.02~0.21) 1.17 (0.94~1.4) 0.79 (0.64~0.93) 1.06 (0.85~1.27) 0.2 (0.14~0.25) −0.02 (−0.13~0.09) 0.08 (0~0.17) −0.05 (−0.12~0.02) −0.25 (−0.36~−0.14) −0.13 (−0.22~−0.04)
East Asia 7.14 (6.4~7.89) 7.96 (7.2~8.72) 7.5 (6.75~8.26) 11.67 (11.02~12.32) 11.46 (10.83~12.08) 11.5 (10.86~12.13) −0.01 (−0.29~0.26) −0.96 (−1.36~−0.55) −0.54 (−0.86~−0.21) −0.17 (−0.28~−0.06) −0.87 (−1.1~−0.64) −0.48 (−0.63~−0.34)
Eastern Europe 7.55 (7.14~7.95) 8.26 (7.68~8.83) 7.75 (7.33~8.16) 8.04 (7.62~8.46) 9.05 (8.44~9.68) 8.39 (7.97~8.81) 2.66 (2.34~2.99) 3.84 (3.44~4.24) 3.46 (3.16~3.77) 3.77 (3.46~4.08) 3.59 (3.26~3.93) 3.79 (3.5~4.08)
Eastern Sub–Saharan Africa 0.03 (−0.07~0.13) −0.03 (−0.09~0.04) −0.02 (−0.1~0.07) 1.72 (1.46~1.98) 0.73 (0.65~0.81) 1.39 (1.19~1.6) −0.09 (−0.14~−0.03) −0.15 (−0.31~0.02) −0.13 (−0.24~−0.02) −0.45 (−0.52~−0.38) −0.52 (−0.71~−0.33) −0.5 (−0.61~−0.38)
High–income Asia Pacific 1.65 (1.45~1.86) 1.51 (1.4~1.62) 1.55 (1.43~1.68) 2.11 (1.99~2.23) 1.39 (1.26~1.53) 1.71 (1.61~1.81) −1.21 (−1.65~−0.78) −0.19 (−0.62~0.25) −0.49 (−0.92~−0.06) −1.83 (−2.26~−1.39) −1 (−1.41~−0.58) −1.32 (−1.74~−0.9)
High–income North America 1.34 (0.82~1.85) 1.58 (1.01~2.15) 1.43 (0.89~1.98) 0.84 (0.3~1.39) 1.15 (0.57~1.74) 1.01 (0.45~1.57) −0.51 (−0.78~−0.24) −0.08 (−0.28~0.12) −0.28 (−0.49~−0.07) −1.43 (−1.78~−1.09) −0.83 (−1.05~−0.61) −1.15 (−1.42~−0.88)
North Africa and Middle East 0.04 (−0.27~0.35) 1.28 (1.09~1.47) 0.42 (0.16~0.68) 1.7 (1.29~2.11) 4.19 (3.93~4.45) 2.19 (1.84~2.55) −0.56 (−0.64~−0.48) −0.69 (−0.77~−0.61) −0.65 (−0.7~−0.61) −0.66 (−0.73~−0.6) −0.75 (−0.82~−0.68) −0.71 (−0.77~−0.65)
Oceania 0.52 (−0.13~1.17) 1.84 (1.51~2.17) 0.9 (0.34~1.45) 2.67 (1.29~4.06) 5.48 (4.85~6.13) 3.44 (2.28~4.62) −0.46 (−0.53~−0.39) 0.14 (0.05~0.24) −0.28 (−0.36~−0.2) −0.28 (−0.35~−0.22) 0.23 (0.15~0.31) −0.13 (−0.19~−0.06)
South Asia 0.29 (0.26~0.32) 0.86 (0.75~0.97) 0.31 (0.26~0.36) 1.48 (1.43~1.53) 2.23 (2.11~2.34) 1.52 (1.49~1.55) −0.09 (−0.17~−0.01) −0.11 (−0.24~0.02) −0.11 (−0.2~−0.01) −0.1 (−0.16~−0.04) −0.07 (−0.18~0.03) −0.12 (−0.19~−0.05)
Southeast Asia 1.39 (1.15~1.63) 1.99 (1.69~2.28) 1.66 (1.39~1.93) 5.82 (5.41~6.22) 6.45 (6.04~6.86) 6.09 (5.69~6.5) 0.31 (0.22~0.4) 0.2 (0.06~0.34) 0.25 (0.13~0.36) 0.15 (0.08~0.21) −0.06 (−0.16~0.04) 0.06 (−0.02~0.14)
Southern Latin America 4.77 (4.4~5.14) 3.24 (2.84~3.64) 3.96 (3.58~4.35) 8.16 (7.46~8.87) 6.67 (6.08~7.26) 7.44 (6.81~8.08) 0.27 (0.13~0.41) −0.34 (−0.43~−0.24) −0.11 (−0.21~−0.01) −0.13 (−0.28~0.02) −0.49 (−0.59~−0.39) −0.33 (−0.45~−0.22)
Southern Sub–Saharan Africa 6.01 (4.87~7.16) −0.5 (−0.56~−0.44) 5.08 (4.01~6.15) 9.62 (8.13~11.14) −0.13 (−0.27~0) 9.15 (7.62~10.7) 0.56 (0.36~0.76) −0.22 (−0.38~−0.07) 0.06 (−0.11~0.23) 0.09 (−0.1~0.28) −0.88 (−1.04~−0.72) −0.41 (−0.58~−0.24)
Tropical Latin America 0.71 (0.52~0.9) 0.23 (0.12~0.34) 0.48 (0.32~0.64) 3.39 (3.11~3.68) 3.28 (3.13~3.43) 3.31 (3.08~3.54) −0.42 (−0.61~−0.22) −0.21 (−0.33~−0.1) −0.36 (−0.51~−0.2) −1.23 (−1.44~−1.01) −0.73 (−0.89~−0.57) −1.05 (−1.25~−0.86)
Western Europe 5.65 (4.96~6.34) 7.12 (6.12~8.12) 6.35 (5.5~7.2) 5.76 (5.03~6.5) 7.4 (6.4~8.41) 6.6 (5.72~7.49) 0.41 (0.31~0.5) 0.55 (0.47~0.64) 0.47 (0.4~0.54) −0.51 (−0.61~−0.4) −0.08 (−0.15~−0.01) −0.31 (−0.38~−0.24)
Western Sub–Saharan Africa −0.06 (−0.11~−0.01) 0.55 (0.51~0.59) −0.03 (−0.07~0.01) 0.98 (0.83~1.13) 1 (0.96~1.03) 0.72 (0.58~0.85) −0.48 (−0.57~−0.39) 0.04 (−0.01~0.08) −0.44 (−0.51~−0.37) −0.57 (−0.67~−0.47) −0.23 (−0.31~−0.15) −0.68 (−0.78~−0.59)

ASIR, the age-standardized incidence rate; ASPR, the age-standardized prevalence rate; ASDR, the age-standardized death rate; ASDALYR, the age-standardized disability-adjusted life years rate; CAVD, calcific aortic valve disease; SDI, socio-demographic index.