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. 2022 Nov 23;14:1056312. doi: 10.3389/fnagi.2022.1056312

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Copyright © 2022 He, Cong, Liang, Ma, Tian, Li and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The results of 2 clusters of patients with AD. (A) Heatmap of consensus clustering for k = 2–9. Colour gradients indicate from 0 to 1 (white: 0, blue: 1). (B) Delta represents the relative change course in the area under the CDF curve when k = 2–9. (C) Cumulative distribution function (CDF); (D) PCA results of the expression profiles of the two FRGcluster patterns, showing the marked differences in the transcriptomes between the different FRGclusters. The red dots in the scatter plot represent FRGcluster A, and the blue dots represent FRGcluster B. CDF, cumulative distribution function; FRGcluster, Ferroptosis-related gene cluster.