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. 2022 Nov 23;14:1056312. doi: 10.3389/fnagi.2022.1056312

FIGURE 6.

FIGURE 6

(A,B) The GO enrichment and KEGG pathway analysis results of CDEGs are shown as circle plots. For enrichment analysis of the circle plot, the GO id (or pathway id) label of the first circle corresponds to the “id” of the result data (Supplementary Table 1), and The “class” of the result data corresponds to the colour of the grouping. The length of the bar in the second circle corresponds to the “bg_num” of the resulting data, i.e., the number of background genes, and the shade of the colour corresponds to the P-value (or Q value). The third circle corresponds to the “fg_num” of the resulting data, i.e., the number of foreground genes. The fourth circle (polar bar) shows the Rich factor, obtained by dividing fg_num and bg_num and corresponds to the data in the ratio column of “Supplementary Table 1”. (C) Cluster-heatmap. (D) Cumulative distribution function (CDF). (E) Delta area plot. (F) Comparison of the percentage of immune cell infiltration between geneCluster A and B; Blue represents FRGcluster A; yellow represents FRGcluster B. *P < 0.05; **P < 0.01; ****P < 0.001. CDEGs, cluster differential expressed genes; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; CDF, cumulative distribution function.