Table 1.
Demographic characteristics and risk factors of healthy controls (HC) and mild cognitive impairment (MCI) patients
| Normal cognition (n = 20) | MCI (n = 20) | P-value | |
|---|---|---|---|
| Age (yr) | 63.95±7.90 | 65.95±8.80 | 0.454 |
| Male | 11 (55.0) | 12 (60.0) | 0.749 |
| Handedness (right/left) | 18 (90.0) | 19 (95.0) | 0.548 |
| Education duration (yr) | 9.85±0.758 | 8.40±0.515 | 0.122 |
| Hypertention | 13 (65.0) | 12 (60.0) | 0.774 |
| Diabetes mellitus | 8 (40.0) | 6 (30.0) | 0.507 |
| Current drinker | 5 (25.0) | 6 (30.0) | 0.723 |
| Current smoker | 8 (40.0) | 8 (40.0) | 1.000 |
| MMSE | 28.10±1.774 | 23.00±3.228 | < 0.01 |
| MoCA | 26.90±2.789 | 19.75±5.628 | < 0.01 |
| Total cholesterol (mg/dL) | 161.150±11.6989 | 175.600±12.2626 | 0.399 |
| Triglyceride (mg/dL) | 1.5940±0.17858 | 2.6900±0.68658 | 0.137 |
| Plasma homocysteine level (μM) | 9.820±0.8865 | 10.730±0.6951 | 0.424 |
| APOE 4 positive | 4 (20.0) | 5 (25.0) | 0.705 |
| Depression (PHQ-9) | 5.45±1.109 | 4.85±1.179 | 0.713 |
| Anxiety (GAD-7) | 3.40±0.622 | 4.15±0.748 | 0.445 |
Data are expressed as number (percentage) or mean ± SD as appropriate.