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. 2022 Jun 2;18(3):535–536. doi: 10.4103/1673-5374.346485

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Copyright: © Neural Regeneration Research

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Beneficial roles of CD34⁺ BMPCs following CNS injury.

CD34⁺ BMPCs and the EPCs subtypes, early and late, can promote both angiogenesis and vasculogenesis following CNS injury by specializing in endothelial cells, and/or indirectly by secreting free and exosome-enveloped growth factors. G-CSF is a glycoprotein that acts in the bone marrow to mobilize both EPCs and CD34⁺ BMPCs after damage. BMPCs: Bone marrow progenitor cells; CNS: central nervous system; EPCs: endothelial progenitor cells; G-CSF: granulocyte colony-stimulating factor. Created with BioRender.com.