Additional Table 3.
The identified ferroptosis DEGs in 1, 3, 7 days post-SCI
| Group | Ferroptosis DEGs | Gene title |
|---|---|---|
| SCI-1d (48 genes) | Aco1 | aconitase 1 |
| Acsl4 | acyl-CoA synthetase long chain family member 4 | |
| Ano6 | anoctamin 6 | |
| Atf3 | activating transcription factor 3 | |
| Aurka | aurora kinase A | |
| Capg | capping actin protein, gelsolin like | |
| Cav1 | caveolin 1 | |
| Cbs | cystathionine beta-synthase | |
| Cd44 | CD44 molecule (Indian blood group) | |
| Chac1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 | |
| Chmp6 | charged multivesicular body protein 6 | |
| Cybb | cytochrome b-245 beta chain | |
| Ddit4 | DNA damage inducible transcript 4 | |
| Enpp2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | |
| Fancd2 | FA complementation group D2 | |
| Fbxw7 | F-box and WD repeat domain containing 7 | |
| Gabarapl1 | GABA type A receptor associated protein like 1 | |
| Gch1 | GTP cyclohydrolase 1 | |
| Gls2 | glutaminase 2 | |
| Got1 | glutamic-oxaloacetic transaminase 1 | |
| Hic1 | HIC ZBTB transcriptional repressor 1 | |
| Hmox1 | heme oxygenase 1 | |
| Hspb1 | heat shock protein family B (small) member 1 | |
| Il33 | interleukin 33 | |
| Jun | Jun proto-oncogene, AP-1 transcription factor subunit | |
| Lpcat3 | lysophosphatidylcholine acyltransferase 3 | |
| Lpin1 | phosphatidate phosphatase lipin 1 | |
| Mapk1 | mitogen-activated protein kinase 1 | |
| Mapk8 | mitogen-activated protein kinase 8 | |
| Mapk9 | mitogen-activated protein kinase 9 | |
| Mt3 | metallothionein 3 | |
| Nras | NRAS proto-oncogene, GTPase | |
| Plin2 | perilipin 2 | |
| Psat1 | phosphoserine aminotransferase 1 | |
| Ptgs2 | phosphoserine aminotransferase 2 | |
| Rela | RELA proto-oncogene, NF-kB subunit | |
| Rgs4 | regulator of G protein signaling 4 | |
| Ripk1 | receptor interacting serine/threonine kinase 1 | |
| Sat1 | spermidine/spermine N1-acetyltransferase 1 | |
| Scd | stearoyl-CoA desaturase | |
| Srxn1 | sulfiredoxin 1 | |
| Stat3 | signal transducer and activator of transcription 3 | |
| Tgfbr1 | transforming growth factor beta receptor 1 | |
| Tlr4 | toll like receptor 4 | |
| Ulk1 | unc-51 like autophagy activating kinase 1 | |
| Vegfa | vascular endothelial growth factor A | |
| Xbp1 | X-box binding protein 1 | |
| Zfp36 | ZFP36 ring finger protein | |
| SCI-3d (44 genes) | Acsf2 | acyl-CoA synthetase family member 2 |
| Acsl4 | acyl-CoA synthetase long chain family member 4 | |
| Agpat3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | |
| Ano6 | anoctamin 6 | |
| Asns | asparagine synthetase (glutamine-hydrolyzing) | |
| Atf3 | activating transcription factor 3 | |
| Atf4 | activating transcription factor 4 | |
| Capg | capping actin protein, gelsolin like | |
| Cbs | cystathionine beta-synthase | |
| Cd44 | CD44 molecule (Indian blood group) | |
| Cdo1 | cysteine dioxygenase type 1 | |
| Chac1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 | |
| Chmp6 | charged multivesicular body protein 6 | |
| Cxcl2 | C-X-C motif chemokine ligand 2 | |
| Cybb | cytochrome b-245 beta chain | |
| Ddit3 | DNA damage inducible transcript 3 | |
| Ddit4 | DNA damage inducible transcript 4 | |
| Enpp2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | |
| Gch1 | GTP cyclohydrolase 1 | |
| Gls2 | glutaminase 2 | |
| Gpx2 | glutathione peroxidase 2 | |
| Hmox1 | heme oxygenase 1 | |
| Hspb1 | heat shock protein family B (small) member 1 | |
| Il33 | interleukin 33 | |
| Il6 | interleukin 6 | |
| Jun | Jun proto-oncogene, AP-1 transcription factor subunit | |
| Klhl24 | kelch like family member 24 | |
| Ngb | neuroglobin | |
| Nras | NRAS proto-oncogene, GTPase | |
| Panx1 | pannexin 1 | |
| Pck2 | phosphoenolpyruvate carboxykinase 2, mitochondrial | |
| Plin2 | perilipin 2 | |
| Psat1 | phosphoserine aminotransferase 1 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | |
| Ripk1 | receptor interacting serine/threonine kinase 1 | |
| Sat1 | spermidine/spermine N1-acetyltransferase 1 | |
| Sesn2 | sestrin 2 | |
| Srxn1 | sulfiredoxin 1 | |
| Stat3 | signal transducer and activator of transcription 3 | |
| Tgfbr1 | transforming growth factor beta receptor 1 | |
| Tlr4 | toll like receptor 4 | |
| Txnrd1 | thioredoxin reductase 1 | |
| Ulk1 | unc-51 like autophagy activating kinase 1 | |
| Zfp36 | ZFP36 ring finger protein | |
| SCI-7d (27genes) | Ano6 | anoctamin 6 |
| Atf3 | activating transcription factor 3 | |
| Aurka | aurora kinase A | |
| Capg | capping actin protein, gelsolin like | |
| Cd44 | CD44 molecule (Indian blood group) | |
| Chmp6 | charged multivesicular body protein 6 | |
| Cybb | cytochrome b-245 beta chain | |
| Fbxw7 | F-box and WD repeat domain containing 7 | |
| Gabarapl1 | GABA type A receptor associated protein like 1 | |
| Gch1 | GTP cyclohydrolase 1 | |
| Gls2 | glutaminase 2 | |
| Got1 | glutamic-oxaloacetic transaminase 1 | |
| Hmox1 | heme oxygenase 1 | |
| Jun | Jun proto-oncogene, AP-1 transcription factor subunit | |
| Lpcat3 | lysophosphatidylcholine acyltransferase 3 | |
| Mapk9 | mitogen-activated protein kinase 9 | |
| Nras | NRAS proto-oncogene, GTPase | |
| Plin2 | perilipin 2 | |
| Rela | RELA proto-oncogene, NF-kB subunit | |
| Rgs4 | regulator of G protein signaling 4 | |
| Ripk1 | receptor interacting serine/threonine kinase 1 | |
| Sat1 | spermidine/spermine N1-acetyltransferase 1 | |
| Srxn1 | sulfiredoxin 1 | |
| Stat3 | signal transducer and activator of transcription | |
| Tgfbr1 | transforming growth factor beta receptor 1 | |
| Tlr4 | toll like receptor 4 | |
| Vegfa | vascular endothelial growth factor A |