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. 2022 Aug 2;18(3):657–663. doi: 10.4103/1673-5374.350212

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Copyright: © Neural Regeneration Research

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Effect of the granular hydrogel nerve guidance conduit on the CMAP of the operation side of the sciatic nerves in rats 16 weeks after surgery.

(A) The CMAP waveforms of the autologous nerve, granular hydrogel, chitosan conduit, and bulk gel conduit groups were recorded in the proximal nerve portion of the stimulation. The peak amplitudes of the CMAP waveforms in the autologous nerve and granular hydrogel groups were the greatest, followed by the chitosan conduit group and bulk hydrogel group. (B) Peak amplitude of CMAP. Data are shown as the mean ± SD (n = 6). ***P < 0.001, vs. Group G; ###P < 0.001, vs. Group A; $$$P < 0.001, vs. Group C (one-way analysis of variance followed by Tukey’s post hoc test). CMAP: Compound muscle action potential; Group A: autologous nerve group; Group B: bulk hydrogel group; Group C: chitosan conduit group; Group G: granular hydrogel group.