Table 1.

Clinical, laboratory features and treatment of patients.

	Case 1	Case 2	Case 3	Case 4
Age(years)/Sex	30/F	26/F	40/F	40/F
SLE duration(years)	0	10	0	20
Treatment at flare	None	5mg PZ HCQ, MTX	None	5mg PZ HCQ
Extra-GI manifestations at flare	Fever, arthritis, pleuritis, pericarditis, cytopenias	Fever, arthritis, pleuritis, cytopenias	Fever, pleuritis	None
Abnormal blood tests	Hb 6.6g/dl WBC 2530/μl CRP 9.4mg/dl ESR 120mm/hr	Hb 10g/dl WBC 3020/μl PLT 127000/μl ALT 439 U/l AST 824 U/l CRP 22 mg/dl ESR 56 mm/hr	Hb 11.6g/dl	None
Serological activity	Yes	Yes	Yes	Yes
Treatment administeredv	1mg/kg PZ HCQ	3gr MP iv 0.6mg/kg PZ Belimumab	3gr MP iv 0.8mg/kg PZ AZA, HCQ	3gr MP iv 1mg/kg PZ CYC iv
Follow-up	No relapse	No relapse	No relapse	No relapse

F: female; PZ: prednisone; HCQ: hydroxychloroquine; MTX: methotrexate; GI: gastrointestinal; iv: intravenous; MP: methylprednisolone; AZA: azathioprine; CYC: cyclophosphamide