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. 2022 Nov 23;13:1066244. doi: 10.3389/fphar.2022.1066244

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Copyright © 2022 Chu, Wang, Jia, Yang, Shi, Cui, Huang, Ye and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FZNZ inhibited MC cell viability and induced cell death. (A) MC and GES-1 cells were incubated with various concentrations of FZNZ for 24 h. Cell viability was determined by CCK8 assay. (B) MC cells were treated with different concentrations of FZNZ for 24 h, and cytotoxicity were evaluated by LDH assay. (C). The percentage of apoptotic MC cells. (D). Representative dot-plots illustrated the apoptotic status of MC cells. Data are shown as the mean ± SD or SEM; N = 3–5/group (*p < 0.05, **p < 0.01, ***p < 0.001).