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. 2022 Sep 29;7(12):2589–2607. doi: 10.1016/j.ekir.2022.09.018

Table 3.

Recommendations for empiric dosing and titration of insulins in CKD97

eGFR % Reduction of TDD Insulin dose (units/kg/d)
T1D T2D
>60 ml/min/1.73 m2 No reduction 1.0 0.5
60–15 ml/min/1.73 m2 25% 0.75 0.3–0.4
<15 ml/min/1.73 m2 50% 0.5 0.25

eGFR, estimated glomerular filtration rate; T1D, type 1 diabetes mellitus; T2D, type 2 diabetes mellitus; TDD, total daily dose.