Table 2.
Patient demographics and clinical and operative characteristics
|
Characteristic
|
Group 1, n = 277
|
Group 2, n = 94
|
Group 3, n = 25
|
P
value
|
| Age, mean ± SD | 68.8 ± 11.3 | 72.2 ± 14.5 | 73.6 ± 13.6 | 0.02a |
| Sex, n (%) | 0.505 | |||
| Male | 161 (58.1) | 59 (62.7) | 17 (68.0) | |
| Female | 116 (41.9) | 35 (37.3) | 8 (32.0) | |
| BMI, mean ± SD | 26.8 ± 3.99 | 26.3 ± 4.05 | 26.0 ± 3.97 | 0.33 |
| CCI, mean ± SD | 5.12 ± 1.83 | 5.55 ± 2.38 | 6.04 ± 2.15 | 0.03a |
| ASA score, n (%) | 0.018a | |||
| I–II | 187 (67.5) | 47 (50.0) | 13 (45.8) | |
| III–IV | 90 (32.5) | 47 (50.0) | 12 (54.2) | |
| Type of surgery, n (%) | 0.071 | |||
| Elective | 238 (86.0) | 72 (76.6) | 19 (75.0) | |
| Urgent | 39 (14.0) | 22 (23.4) | 6 (25.0) | |
| Surgical approach, n (%) | < 0.001a | |||
| Open | 25 (9.0) | 15 (16.0) | 2 (8.0) | |
| Laparoscopic | 238 (86.0) | 72 (77.0) | 15 (60.0) | |
| Conversion | 14 (5.0) | 7 (7.4) | 8 (32.0) | |
| Procedure, n (%) | 0.739 | |||
| Right colectomy1 | 138 (49.8) | 47 (50.0) | 11 (44.0) | |
| Left colectomy | 17 (6.1) | 7 (7.4) | 1 (4.0) | |
| Sigmoid/RS resection | 55 (19.8) | 15 (15.9) | 4 (16.0) | |
| Low anterior resection | 48 (17.3) | 16 (17.0) | 8 (32.0) | |
| Other | 19 (6.8) | 9 (9.6) | 1 (4.0) | |
| Level of anastomosis, n (%) | 0.66 | |||
| Ileocolic | 150 (54.1) | 50 (53.2) | 11 (44.0) | |
| Colocolic | 23 (8.3) | 5 (5.3) | 1 (4.0) | |
| ≥ 6 cm from AV | 67 (24.2) | 25 (26.6) | 10 (40.0) | |
| < 6 cm from AV | 37 (13.4) | 14 (14.9) | 3 (12.0) | |
| Covering stoma, n (%) | 23 (8.3) | 8 (8.51) | 2 (8.0) | 0.99 |
| Blood loss in mL, mean ± SD | 51.6 ± 36.6 | 58.8 ± 47.7 | 104.0 ± 191.1 | < 0.001a |
| Intraoperative complications, n (%) | 3 (1.1) | 5 (5.3) | 4 (16.0) | < 0.001a |
| Operative time in min, mean ± SD | 141.9 (48.3) | 146.2 (50.0) | 172.8 (57.2) | 0.011a |
| LOHS in d | < 0.001a | |||
| mean ± SD | 7.4 ± 2.1 | 14.3 ± 7.4 | 24.0 ± 14.0 | |
| Median | 7 | 13 | 21 | |
| 90-d mortality, n (%) | 0 (0) | 0 (0) | 3 (12.0) | < 0.001a |
a
P < 0.05.
1
Included ileocecal resection/extended right-sided colectomy.
Group 1: No complications; Group 2: Complications not related to colorectal anastomotic leakage; Group 3: Colorectal anastomotic leakage. ASA: American Society of Anesthesiologists; AV: Anal verge; BMI: Body mass index; CCI: Charlson Classification Index; LOHS: Length of hospital stay; RS: Rectosigmoid; SD: Standard deviation.