Table 1.
Comparison of demographic and clinicopathologic characteristics in patients with anastomotic leakage and controls, n (%)
|
Variable
|
Controls (n = 78)
|
AL patients (n = 78)
|
P
value
|
| Male sex | 57 (71.3) | 57 (71.3) | 1.000 |
| Age, mean (SD), yr | 58.23 (9.46) | 56.82 (10.54) | 0.380 |
| Height, mean (SD), cm | 166.23 (7.92) | 166.87 (7.34) | 0.601 |
| Weight, mean (SD), kg | 63.41 (11.62) | 65.40 (11.39) | 0.282 |
| Operative time, mean (SD), min | 207.17 (40.80) | 225.03 (55.29) | 0.023 |
| Laparoscopic surgery | 77 (98.7) | 76 (97.4) | 1.000 |
| Location of tumor, mean (SD), cm | 7.86 (3.39) | 8.22 (3.59) | 0.507 |
| Intraperitoneal chemotherapy | 50 (64.1) | 54 (69.2) | 0.497 |
| Cleansing enema | 57 (73.1) | 60 (76.9) | 0.579 |
| Indwelling trans-anal tube | 73 (93.6) | 68 (87.2) | 0.174 |
| Indwelling drainage tube | 72 (92.3) | 74 (94.9) | 0.746 |
| Tumorous obstruction | 1 (1.3) | 6 (7.7) | 0.053 |
| Cigarette smoking | 24 (30.8) | 35 (44.9) | 0.098 |
| Alcohol use | 14 (17.9) | 21 (26.9) | 0.249 |
| Hypertension | 20 (25.6) | 19 (24.4) | 1.000 |
| Diabetes | 10 (12.8) | 11 (14.1) | 1.000 |
| Previous abdominal surgery | 11 (14.1) | 5 (6.4) | 0.186 |
| Preoperative antibiotics | 75 (76.2) | 72 (92.3) | 0.303 |
| Hemoglobin, mean (SD), g/L | 132.60 (16.31) | 123.32 (21.17) | 0.003 |
| Albumin, mean (SD), g/L | 40.52 (3.97) | 38.34 (4.01) | 0.001 |
| Neoadjuvant therapy | 1 (1.3) | 3 (3.8) | 0.620 |
| Tumor size, mean (SD), cm | 2.76 (1.28) | 4.07 (1.36) | < 0.001 |
| ASA score | 0.049 | ||
| 1 | 17 (21.86) | 9 (11.5) | |
| 2 | 56 (71.8) | 56 (71.8) | |
| 3 | 5 (6.4) | 13 (16.7) | |
| Stage | < 0.001 | ||
| 1 | 67 (85.9) | 19 (24.4) | |
| 2 | 5 (6.4) | 33 (42.3) | |
| 3 | 6 (7.7) | 26 (33.3) | |
| Number of linear stapler firings | 0.393 | ||
| 1 | 38(48.7) | 37 (47.4) | |
| 2 | 39 (50.0) | 37 (47.4) | |
| 3 | 1 (1.3) | 4 (5.1) | |
| Stoma | 20 (25.6) | 18 (23.1) | 0.852 |
SD: Standard deviation; ASA: American Society of Anesthesiologists; AL: Anastomotic leakage.