Table 9.
Nanosystem-based PTT/PDT clinical trials in the last 10 years.
| Clinical Trials Types | Condition | Intervention/Treatment/Drug | Status | ClinicalTrials.gov Identifier |
|---|---|---|---|---|
| PTT | Head and Neck Cancer | AuroLase Therapy (silica core coated surrounded by an Au shell) | Completed: August 2014 | NCT00848042 |
| Terminated: June 2014 |
NCT01679470 | |||
| Completed: October 2020 | NCT02680535 | |||
| Neoplasms of the Prostate | AuroShell (silica core coated surrounded by an Au shell) particle infusion | To be completed: June 2023 | NCT04240639 | |
| PDT | Actinic Keratosis | BF-200 ALA gel (nanoemulsion) | Completed: April 2015 | NCT01966120 |
| PDT Microvesicle Particle | Cream containing 4% Imipramine | To be completed: September 2022 | NCT03960125 | |
| Neoplasms, Basal Cell Carcinoma, Basal Cell Photochemotherapy Photosensitizing Agents |
Hexylaminolevulinate cream, Aminolevulinic Acid Nano Emulsion & Methylaminolevulinate cream | To be completed: December 2025 | NCT02367547 | |
| Blastic Plasmacytoid Dendritic Cell Neoplasm Acute Myeloid Leukemia Acute Lymphocytic Leukemia Myeloproliferative Neoplasm |
IMGN632 injection (Targeted antibody-drug conjugate) | To be completed: December 2022 | NCT03386513 |