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. 2022 Winter;21(4):ar71. doi: 10.1187/cbe.21-11-0316
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1 Our hypothesis was that [fast-mutating strain] E938, which is Mut-, would show increased mutation over [the slow-mutating] strain E939.
2 This hypothesis was supported by both our individual and class data.
3 The increased mutation rate and survival of E938 can be attributed to the faulty DNA repair of the Mut− strain.
4 Increased mutation rate allows more bacteria of this strain to gain the traits necessary for survival on the rifampicin plates.
5 E938 also adapts better for the use of lactose as an energy source on the MacConkey agar.