Fig. 5.

FABP3 and FABP5, but not FABP7, accumulate in the mitochondria of ischemic neurons. (A–C) Representative Western blots (A). Quantitative analyses of FABP3 (B) and FABP5 (C) protein expression in the mitochondrial fraction. (D–F) Representative Western blots (D). Quantitative analyses of FABP3 (E) and FABP5 (F) protein expression in the cytosolic fraction. The data shown in each column represent the mean ± SEM. *p < 0.05, **p < 0.01 vs. vehicle-treated sham group (contralateral/ipsilateral); ^#p < 0.05, ^##p < 0.01 vs. vehicle-treated I/R group (contralateral/ipsilateral) (n = 4). (G) Representative immunofluorescence staining of FABP3 (green), TOM20 (red) and DAPI (blue); FABP5 (green), TOM20 (red) and NeuN (blue) in cortical penumbra of I/R mice. Scale bar = 100 μm. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)