Four-component synthesis of chromene-based 2(1H)-pyridones 11 and their in vitro antibacterial activity against three bacterial strains^a.

Compound	R	Inhibition zone (mm)
		BS	EF	ST
11a	C6H5	12	11	—
11b	4-OHC6H4	13	9	8
11c	4-MeOC6H4	12	10	12
11d	4-Me2NC6H4	10	10	11
Ampicillinb	—	25	20	13
Chloramphenicolb	—	24	23	18

^aBS (Bacillus subtilis), EF (Enterococcus faecalis), ST (Salmonella typhimurium).

^bStandard drug for the study.