Skip to main content
. 2022 Nov 17;10(48):15726–15734. doi: 10.1021/acssuschemeng.2c04092

Table 2. Gold(III)-Catalyzed Cyclization of the Internal Alkyne N-Propargylbenzamide (7).

graphic file with name sc2c04092_0007.jpg

entry catalyst product yield (%)a
1 1a 10 8
2 2a 10 ∼1
3 1b 8 72
4 2b 8 81
5 AuCl3 8 and 9 65:30
a

Yields are reported as isolated yields following purification by flash column chromatography. Where only one product is shown, only trace quantities of the other products (8–10) could be identified in the crude mixture by 1H NMR analysis.