TABLE 2:
Microtubule-dependent ATPase Michaelis-Menten fits. Corresponding values for the Michaelis-Menten fits in the plots in Figure 5 D-F. Reported values for kcat and KM are fit ± 95% confidence interval. DMSO control was done using the same volume as used in the 30 μM trial.
| Compound | Compound concentration | kcat (s–1) | Km (μM) |
| DMSO | Equal volume* | 13.8 ± 2 | 4.1 ± 1 |
| Fift-IN | 20 μM | 10.8 ± 2 | 5.4 ± 1 |
| 30 μM | 14.2 ± 9 | 13.2 ± 11 | |
| Munesib-1 | 3 μM | 8.5 ± 1 | 5.9 ± 1 |
| 5 μM | 8.2 ± 3 | 6.1 ± 3 | |
| 30 μM | 11.6 ± 6 | 17 ± 10 | |
| Munesib-2 | 5 μM | 9.0 ± 1 | 4 ± 1 |
| 30 μM | 8.1 ± 5 | 7 ± 7 |