Table 1.
Clinical characteristics of participants with and without hyperthyroidism
| Variable | Controls | Hyperthyroidism | P |
|---|---|---|---|
| n = 100 | n = 88 | ||
| Sex, male, n (%) | 18 (18.0) | 20 (22.7) | 0.421 |
| Age, years | 40.89 ± 10.99 | 40.28 ± 12.96 | 0.729 |
| BMI, kg/m2 | 24.23 ± 4.11 | 21.94 ± 3.43 | < 0.001 |
| TC, mmol/L | 5.13 ± 0.94 | 3.52 ± 0.58 | < 0.001 |
| HDL-C, mmol/L | 1.38 ± 0.37 | 1.14 ± 0.25 | < 0.001 |
| LDL-C, mmol/L | 3.26 ± 0.99 | 1.94 ± 0.60 | < 0.001 |
| TG, mmol/L | 1.14 (0.81, 1.93) | 1.13 (0.83, 1.50) | 0.239 |
| FBG, mmol/L | 5.04 (4.73, 5.34) | 5.11 (4.72, 5.61) | 0.308 |
| FINS, uIU/mL | 9.3 (6.5, 13.4) | 10.9 (7.4, 15.9) | 0.139 |
| HOMA-IR | 2.24 (1.39, 3.38) | 2.59 (1.64, 3.50) | 0.182 |
| eGFR, mL/min/1.73 m2 | 111.3 ± 12.88 | 129.3 ± 17.06 | < 0.001 |
| FT3, pg/mL | 3.28 (3.03, 3.47) | 14.57 (8.92, 20.00) | < 0.001 |
| FT4, ng/dL | 1.26 (1.15, 1.38) | 4.50 (2.90, 6.31) | < 0.001 |
| TSH, μIU/mL | 1.88 (1.35, 2.50) | 0.01 (0.01, 0.01) | < 0.001 |
| Metrnl, pg/mL | 190.3 (165.4, 214.4) | 227.2 (192.3, 289.2) | < 0.001 |
Data were expressed as the mean ± SD or median (interquartile range) unless stated otherwise
BMI body mass index, TG triglycerides, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, FBG fasting blood glucose, FINS fasting insulin, eGFR estimated glomerular filtration rate, FT3 free triiodothyronine, FT4 serum free thyroxine, TSH thyroid-stimulating hormone, Metrnl Meteorin-like
Bold indicates P value < 0.05