Table 2.
Laboratory analysis
| Laboratory Parameters | All patients a (n = 400) | Survivors b (n = 323, 81%) | Deceased b (n = 77, 19%) | p-value c |
|---|---|---|---|---|
| Troponin I (Mic gr/L) | 0.1 (0.1–0.1) | 0.1 (0.1–0.1) | 0.1 (0.1–0.1) | 0.092 |
| WBC count (10^3/µL) | 7.4 (6–9) | 7.3 (6–9) | 8 (6–10) | 0.142 |
| RBC count (10^6/ µL) | 4.4 (3.8–4.8) | 4.4 (4–4.8) | 3.9 (3.5–4.8) | 0.004 |
| Hemoglobin (g/dL) | 12.0 (10.7–13.5) | 12.5 (10.9–13.7) | 11.2 (9.5–12.4) | p < 0.001 |
| Hematocrit (%) | 36 (32–40) | 37 (33–40) | 33 (30–37) | P < 0.001 |
| MCV (f lit) | 84 (78–89) | 85 (78–89) | 83 (78–87) | 0.098 |
| MCH (Pg) | 28 (25–29) | 28 (25–30) | 27 (25–28) | 0.003 |
| MCHC (g/dL) | 33 (32–34) | 33 (32–34) | 32 (31–33) | 0.018 |
| RDW-CV (fL) | 14 (13–16) | 14 (13–16) | 16 (14–17) | P < 0.001 |
| Platelet count (10^3/µL) | 187 (155–231) | 186 (155–231) | 200 (152–235) | 0.425 |
| PT(sec) | 13.8 (13–16) | 13.7 (13–15) | 14.8 (13–17) | 0.161 |
| PTT (sec) | 33 (30–38) | 33 (30–38) | 34 (30–39) | 0.244 |
| INR (Index) | 1.2 (1–1.5) | 1.2 (1–1.4) | 1.3 (1.1–1.7) | 0.183 |
| Random BS (mg/dL) | 120 (96–173) | 120 (95–170) | 118 (101–183) | 0.305 |
| Sodium (mEq/dL) | 139 (136–141) | 139 (137–141) | 137 (133–140) | 0.347 |
| Potassium (mEq/dL) | 4.3 (4–4.6) | 4.2 (4–4.6) | 4.4 (4–5) | 0.465 |
| BUN (mg/dL) | 21 (16–28) | 20 (16–27) | 21 (16–35) | 0.121 |
| Creatinine (mg/dL) | 1.1 (0.9–1.4) | 1.1 (0.9–1.3) | 1.2 (1–1.4) | 0.051 |
| SGOT (mg/dL)* | 22 (17–35) [150] | 22 (17–32) | 31 (18–57) | 0.081 |
| SGPT (IU/L)* | 22 (14–38) [150] | 20 (14–35) | 29 (17–84) | 0.064 |
| ALP (mg/dL)* | 188 (153–251) [144] | 182 (150–248) | 194 (176–270) | 0.074 |
| Albumin (mg/dL)* | 3.9 (3.6–4.2) [134] | 4 (3.7–4.2) | 3.6 (3.3–4) | 0.128 |
| Globulin (g/dL)* | 2.4 (2.1–2.9) [108] | 2.4 (2.1–2.8) | 2.9 (2.3–3.2) | 0.506 |
| Total protein (g/dL)* | 6.5 (6-6.8) [108] | 6.5 (6.1–6.8) | 6.5 (5.8–6.8) | 0.709 |
| Total bilirubin (mg/dL)* | 0.9 (0.5–1.3) [115] | 0.8 (0.5–1.3) | 1.15 (0.7–2.2) | 0.075 |
| Direct bilirubin (mg/dL)* | 0.3 (0.2–0.5) [119] | 0.3 (0.2–0.4) | 0.5 (0.3–0.7) | 0.064 |
| Triglyceride (mg/dL)* | 98 (71–121) [163] | 100 (73–124) | 84 (66–100) | 0.053 |
| Cholesterol (mg/dL)* | 135 (104–164) [162] | 138 (116–161) | 109 (90–167) | 0.145 |
| HDL-CH (mg/dL)* | 37 (30–43) [156] | 38 (32–43) | 36 (23–45) | 0.293 |
| LDL-C (mg/dL)* | 74 (49–98) [156] | 76 (50–98) | 54 (48–95) | 0.204 |
| Uric acid (mg/dL)* | 7.8 (5.6–9.5) [109] | 7.0 (5.3–8.7) | 9.8 (8.3–12.2) | P < 0.001 |
| Ck-mb (IU/L)* | 14 (11–20) [130] | 13 (10–17) | 17 (12–29) | 0.152 |
WBC White blood cell ; RBC Red blood cells; MCV Mean corpuscular volume; MCH Mean corpuscular hemoglobin; MCHC Mean corpuscular hemoglobin concentration; RDW Red blood cell distribution width; PT Prothrombin time; PTT Partial thrombin time; INR international normalized ratio; BS Blood sugar; BUN Blood urea nitrogen; SGOT Serum glutamic oxaloacetic transaminase; SGPT Serum glutamic pyruvic transaminase; ALP Alkaline phosphatase; HDL High-density lipoprotein; LDL Low-density lipoprotein; CK-MB Creatine kinase-MB
a Laboratory parameters were represented by Median (first quartile-third quartile)
b Comparing the groups of patients was tested using the Mann–Whitney U test or the Student’s t-test depending on the distribution normality of the variables, and illustrated by Median (first quartile-third quartile)
c All statistically significant p values (p < 0.05) are in bold
* Shows laboratory parameters that were not requested for all patients. The number of patients from which statistics was calculated is shown in a bracket in front of the quartiles