Table 4.
Cox proportional hazard regression of time to long term mortality
| Variables | Long-term mortality | |||
|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | |||
| HR (95% CI) 2 | P 1 | HR (95% CI) 2 | P 1 | |
| Age | 1.017 (0.997; 1.036) | 0.090 | 1.013 (0.993; 1.034) | 0.206 |
| Men* | 0.970 (0.573; 1.640) | 0.908 | 1.138 (0.644; 2.011) | 0.655 |
| BMI | 1.092 (1.017; 1.219) | 0.015 | 1.098 (1.018; 1.186) | 0.016 |
| Ejection fraction | 0.985 (0.966; 1.005) | 0.145 | 0.988 (0.966; 1.011) | 0.297 |
| SBP | 0.993 (0.983; 1.003) | 0.176 | 0.996 (0.984; 1.007) | 0.476 |
| Etiology of HF* | 0.297 | 0.438 | ||
| Infection | 1.976 (0.535; 7.299) | 0.307 | 1.565 (0.413; 5.935) | 0.510 |
| Hypertensive | 2.115 (0.529; 8.456) | 0.290 | 1.728 (0.421; 7.088) | 0.448 |
| Cardiac arrhythmia | 3.275 (0.989; 10.84) | 0.052 | 2.562 (0.752; 8.722) | 0.132 |
| Valvular heart disease | 3.109 (0.778; 12.43) | 0.109 | 2.805 (6.679; 11.58) | 0.154 |
| Ischemic heart disease | 1.819 (0.483; 6.856) | 0.377 | 1.442 (0.366; 5.678) | 0.601 |
| Type HF(De novo)* | 0.898 (0.509; 1.584) | 0.710 | 1.056 (0.580; 1.925) | 0.858 |
| RBC count | 0.782 (0.552; 1.108) | 0.166 | 0.841 (0.335; 1.347) | 0.712 |
| Hemoglobin | 0.878 (0.782; 0.986) | 0.028 | 0.728 (0.553; 0.958) | 0.024 |
| Hematocrit | 0.945 (0.905; 0.986) | 0.010 | 0.875 (0.759; 1.009) | 0.066 |
| MCV | 0.982 (0.953; 1.012) | 0.230 | 1.007 (0.952; 1.066) | 0.805 |
| MCH | 0.922 (0.855; 0.994) | 0.033 | 0.998 (0.798; 1.119) | 0.916 |
| MCHC | 0.761 (0.640; 0.905) | 0.002 | 0.795 (0.641; 0.987) | 0.037 |
| RDW-CV | 1.202 (1.101; 1.312) | p < 0.001 | 1.174 (1.046; 1.317) | 0.006 |
BMI Body mass index; SBP Systolic blood pressure; HF Heart failure; RBC Red blood cell; MCV Mean corpuscular volume; MCH Mean corpuscular hemoglobin; MCHC Mean corpuscular hemoglobin concentration; RDW Red blood cell distribution width.
All statistically significant p values (p < 0.05) are in bold.
1 Statistical significance of hazard ratio.
2 Hazard ratio calculated by multivariate Cox proportional hazard regression for long-term mortality and its 95% confidence interval.
* Women, dilated cardiomyopathy, and decompensated heart failure were considered the constant values for the sex, etiology, and type of heart failure, respectively.