Appendix Figure S5. MALAT1 knockdown has no effect on photoreceptors and bipolar cells in diabetic retinas.

• A, B
  Three‐month‐old male Sprague–Dawley (SD) rats received an intravitreous injection of scrambled (Scr) shRNA or MALAT1 (M) shRNA, or left untreated for 1 week. Then, the diabetic models were built. Six months after diabetes induction, retinal slices were stained with rhodopsin (Rho, A) or PKCα (B) to label photoreceptors and bipolar cells. Data are presented as mean ± standard deviation (SD), n = 5 animals per group; scale bar, 100 μm; one‐way ANOVA followed by Dunnet's multiple comparison test. For rhodopsin: P = 0.506 (DR vs. Wt), P = 0.663 (DR + Scr vs. Wt), P = 0.783 (DR + M vs. Wt), P = 0.312 (DR + Scr vs. DR), P = 0.718 (DR + M vs. DR), and P = 0.524 (DR + M vs. DR + Scr). For PKCα: P = 0.271 (DR vs. Wt), P = 0.178 (DR + Scr vs. Wt), P = 0.330 (DR + M vs. Wt), P = 0.641 (DR + Scr vs. DR), P = 0.669 (DR + M vs. DR), and P = 0.498 (DR + M vs. DR + Scr). The representative images of one replicate experiment and statistical results were shown.