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. 2022 Nov 29;99(22):e2454–e2463. doi: 10.1212/WNL.0000000000201205

Figure 2. Random-Effects Meta-analysis of Raw Mean WMH Volume Change in Milliliters Over Median of 2 Years, Range 0.25–8.1 Years.

Figure 2

Squares represent means and bars the 95% CI. AD = Alzheimer disease; CAA = cerebral amyloid angiopathy; DLB = Lewy body dementia; DM = diabetes mellitus; healthy/CD = healthy/community-dwelling; MDD = major depressive disorder; MRAW = raw means; PDD = Parkinson disease dementia; SVD = small vessel disease; VRF = vascular risk factor; WMH = white matter hyperintensity.