Table 6.

Drugs Approved by the FDA for Weight Loss^*

Generic Name, Year of Approval	Trade Name(s)	Dose	DEA Schedule
Pancreatic lipase inhibitor approved by the FDA for long-term use (≥12 mo)
Orlistat,1999	Xenical	120 mg 3 times daily before meals	Not scheduled
Orlistat, 2007	Alli (over the counter)	60 mg 3 times daily before meals	Not scheduled
Serotinin-2C receptor agonist approved by the FDA for long-term use (12 mo)
Lorcaserin, 2012	Belviq	10 mg twice daily	IV
Combination of phentermine-topiramate approved by the FDA for long-term use (12 mo)
Phentermine-topiramate, 2012	Qsymia	3.75/23 mg 7.5/46 mg 15/92 mg	IV
Noradrenergic drugs approved for short-term use (usually <12 wk)
Diethylpropion, 1959	Tenuate Tenuate Dospan	25 mg 3 times a day 75 mg every morning	IV
Phentermine, 1959	Adipex and many others	15–30 mg/d	IV
Benzphetamine, 1960	Didrex	25–50 mg 3 times daily	III
Phendimetrazine, 1959	Bontril Prelu-2	17.5–70 mg 3 times daily 105 mg daily	III

DEA indicates US Drug Enforcement Administration; and FDA, US Food and Drug Administration.

^*Side effect profiles can be found in the package inserts for each agent.