Fig. 4. Time-kill curves of Bacillus brevis GZDF3 siderophore to C. albicans.

C. albicans were cultured in the potato dextrose broth (PDB) medium. Different concentrations siderphore which was purified by Fe(III)-IMAC column were add to the medium according to the figure. PDB medium-only group (Medium) used as negative control. C. albicans with PDB medium (Bacteria Solution) is control group. And the amphotericin B (AMB) used as posititive control according to the figure. Then samples were detected by at different time points as described in the figure. OD600 value represents bacteria concentration of C. albicans. Error bars represent standard deviations of three replicates.