Table 1.
Antiviral activity (IC50), cell toxicity (CC50), and selectivity index (SI) of 10 compounds selected by the primary screening with remdesivir as a positive control.
| Drug name | IC50 (µM) | CC50 (µM) | Selectivity Index (SI) |
|---|---|---|---|
| Flunarizine | 5.3 | >100 | >18.9 |
| Micafungin | 5.5 | >100 | >18.1 |
| Amodiaquine | 5.8 | >100 | >17.2 |
| Meclizine | 5.6 | >100 | >17.9 |
| Lomerizine | 12.8 | >100 | >7.8 |
| Buclizine | 19.6 | >100 | >5.1 |
| Beclamide | 72 | >100 | >1.4 |
| Losartan | 72 | >100 | >1.4 |
| Salinomycin | 0.58 | 56.3 | 97.1 |
| Celecoxib | 17.5 | 74.8 | 4.3 |
| Remdesivir | 5.0 | >100 | >20 |