Fig. 5.

Effect of Undaria pinnatifida fucoidan-rich extract (DSU02) on the production of TNF-α, IFN-γ, IgM, and total IgG in CPtreated immunosuppressed mice. Mice were intraperitoneally injected with 80 mg/kg of cyclophosphamide (CP) and subsequently administered with either drinking water (DW), RG extract (10 mg/kg), or one of three different doses of Undaria pinnatifida fucoidan-rich extract (DSU02 50 mg/kg, 100 mg/kg, 150 mg/kg). Whole blood was drawn at the experimental end point and the productions of TNF-α (A), IFN-γ (B), IgM (C), and total IgG (D) were measured using ELISA. Significant difference is shown: *p < 0.05.