FIG. 2.

Effect of anti-CD40L on production of IL-12 and IFN-γ during toxoplasmosis. Splenocytes and BMNC were isolated from C57BL/6 mice, cells were stimulated in vitro for 48 h with TLA in the presence of an isotype control antibody (Iso) or anti-CD40L, and the levels of IL-12 (A) and IFN-γ (B) were measured by ELISA. For mice infected for 5 days the results are the means plus SEs of the pooled data from five experiments with three to five mice per experiment. For mice infected for 10 weeks the data are the means plus SEs of the pooled data from three experiments.