Table 1. Counts of matches between our inferred responsive yellow fever (YFV) sequences and either (YFV) or cytomegalovirus (CMV) sequences obtained from VDJdb, where the CMV sequences are used as a control. Also provided are analogous counts for responsive sequences inferred by Pogorelyy et al. [20]. Columns S1—Q2 correspond to the six subjects discussed in [20], also discussed in the Materials and Methods section.
Method | Antigen | S1 | S2 | P1 | P2 | Q1 | Q2 | Total |
---|---|---|---|---|---|---|---|---|
Ours (exact match) | CMV | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Ours (is in a top-10 cluster) | CMV | 2 | 2 | 4 | 4 | 4 | 12 | 28 |
Ours (exact match) | YFV | 1 | 1 | 1 | 0 | 0 | 0 | 3 |
Ours (is in a top-10 cluster) | YFV | 28 | 20 | 18 | 11 | 2 | 14 | 93 |
Pogorelyy (exact match) | CMV | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pogorelyy (1 CDR3aa mismatch) | CMV | 0 | 0 | 0 | 1 | 0 | 2 | 3 |
Pogorelyy (2 CDR3aa mismatch) | CMV | 5 | 5 | 5 | 3 | 2 | 10 | 30 |
Pogorelyy (exact match) | YFV | 3 | 5 | 2 | 1 | 3 | 4 | 18 |
Pogorelyy (1 CDR3aa mismatch) | YFV | 24 | 10 | 12 | 9 | 5 | 21 | 81 |
Pogorelyy (2 CDR3aa mismatch) | YFV | 27 | 30 | 24 | 11 | 40 | 21 | 153 |