TABLE 2.
Baseline characteristics of the study population.
| All (n = 766) | Control (n = 274) | CAD (n = 492) | P-value | |
| Age (years) | 61.4 ± 9.8 | 58.3 ± 9.7 | 63.2 ± 9.4 | 0.000 |
| Male (%) | 494 (64.5%) | 131 (47.8%) | 363 (73.8%) | 0.000 |
| BMI (kg/m2) | 25.0 ± 3.3 | 25.0 ± 3.6 | 25.1 ± 3.2 | 0.470 |
| Smoking (%) | 213 (27.8%) | 57 (20.8%) | 156 (31.7%) | 0.001 |
| Drinking (%) | 92 (12.0%) | 32 (11.7%) | 60 (12.2%) | 0.908 |
| Diabetes (%) | 181 (23.6%) | 34 (12.4%) | 147 (29.9%) | 0.000 |
| Hypertension (%) | 473 (61.7%) | 155 (56.6%) | 318 (64.6%) | 0.030 |
| SBP (mmHg) | 136.1 ± 19.8 | 132.0 ± 17.9 | 138.3 ± 20.5 | 0.000 |
| DBP (mmHg) | 76.7 ± 11.4 | 77.6 ± 11.2 | 76.3 ± 11.5 | 0.186 |
| WBC (109/L) | 6.2 (5.3–7.3) | 6.0 (5.1–7.1) | 6.4 (5.3–7.4) | 0.001 |
| Neutrophils (109/L) | 3.6 (2.9–4.5) | 3.4 (2.7–4.2) | 3.7 (3.1–4.7) | 0.000 |
| CRP (mg/L) | 0.8 (0.4–2.1) | 0.8 (0.4–1.9) | 0.9 (0.4–2.7) | 0.065 |
| FBG (mmol/L) | 5.1 (4.6–6.0) | 4.9 (4.6–5.4) | 5.2 (4.6–6.3) | 0.000 |
| PBG (mmol/L) | 7.5 (6.0–10.5) | 6.8 (5.6–8.4) | 8.2 (6.3–11.9) | 0.000 |
| HbA1c (%) | 5.9 (5.6–6.6) | 5.8 (5.5–6.1) | 6.0 (5.7–7.1) | 0.000 |
| TC (mmol/L) | 4.1 (3.5–4.9) | 4.3 (3.6–5.1) | 4.0 (3.4–4.8) | 0.001 |
| TG (mmol/L) | 1.5 (1.1–2.0) | 1.5 (1.1–2.0) | 1.4 (1.1–2.0) | 0.868 |
| HDL-C (mmol/L) | 1.0 (0.9–1.2) | 1.1 (0.9–1.3) | 1.0 (0.9–1.2) | 0.000 |
| LDL-C (mmol/L) | 2.4 (1.8–3.0) | 2.6 (1.9–3.1) | 2.3 (1.8–3.0) | 0.028 |
| Creatinine (umol/L) | 78.0 (68.0–87.0) | 73.0 (64.0–83.0) | 80.0 (70.0–90.0) | 0.000 |
| eGFR | 87.9(76.7–96.1) | 90.5(81.2–98.3) | 86.1(74.4–94.8) | 0.000 |
| NHR | 3.5 (2.6–4.6) | 3.2 (2.3–4.2) | 3.7 (2.8–4.9) | 0.000 |
| LDL-C/HDL-C | 2.3 (1.7–3.1) | 2.2 (1.7–3.0) | 2.4 (1.8–3.1) | 0.102 |
| Medications | ||||
| Aspirin (%) | 650 (84.9%) | 206 (75.2%) | 444 (90.2%) | 0.000 |
| Statins (%) | 629 (82.1%) | 166 (60.6%) | 463 (94.1%) | 0.000 |
| Hypoglycemic drugs (%) | 140 (18.3%) | 29 (10.6%) | 111 (22.6%) | 0.000 |
Data were expressed as mean ± standard deviation for normally distributed continuous variables, median (interquartile range) for abnormally distributed variables and number (%) for category variables. For comparisons between groups, the independent samples t-test was applied for normally distributed continuous variables and Mann–Whitney U test was used for skewed data. For categorical data, χ2 test or Fisher’s exact test were used to test the differences between groups.
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell; CRP, C reactive protein; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; eGFR, estimated Glomerular Filtration Rate; FBG, fasting blood glucose; PBG, postprandial blood glucose; HbA1c, hemoglobin A1c.
Statin includes rosuvastatin, simvastatin, pravastatin, etc. Hypoglycemic drugs include metformin, sulfonylureas, glucosidase inhibitors, glinides.