TABLE 3.
Baseline characteristics of the participants stratified by tertiles of Gensini score.
| Gensini score |
||||
| Tertile 1 (≤ 24) | Tertile 2 (24–45) | Tertile 3 (≥ 45) | P-trend | |
| n (%) | 180 (36.6%) | 149 (30.3%) | 163 (33.1%) | / |
| Age (years) | 62.1 ± 8.9 | 64.1 ± 9.9 | 63.5 ± 9.5 | 0.146 |
| Male (%) | 129 (71.7%) | 107 (71.8%) | 127 (77.9%) | 0.341 |
| BMI (kg/m2) | 24.7 ± 3.3 | 24.7 ± 2.9 | 25.8 ± 3.3*# | 0.001 |
| Smoking (%) | 64 (35.6%) | 39 (26.2%) | 53 (32.5%) | 0.184 |
| Drinking (%) | 35 (19.4%) | 15 (10.1%) | 10 (6.1%)* | 0.001 |
| Diabetes (%) | 42 (23.3%) | 42 (28.2%) | 63 (38.7%)* | 0.007 |
| Hypertension (%) | 115 (63.9%) | 98 (65.8%) | 105 (64.4%) | 0.936 |
| SBP (mmHg) | 137.3 ± 21.9 | 138.9 ± 18.5 | 138.9 ± 20.7 | 0.695 |
| DBP (mmHg) | 75.7 ± 11.3 | 76.2 ± 11.5 | 76.9 ± 11.7 | 0.650 |
| WBC (10^9/L) | 6.1 (5.1–7.2) | 6.2 (5.1–7.2) | 6.9 (5.7–8.1)*# | 0.000 |
| Neutrophils (10^9/L) | 3.5 (2.9–4.3) | 3.5 (3.0–4.6) | 4.1 (3.4–5.2)*# | 0.000 |
| CRP (mg/L) | 0.6 (0.4–1.6) | 0.9 (0.5–2.0) | 1.5 (0.6–4.3)* | 0.000 |
| FBG (mmol/L) | 5.1 (4.6–6.0) | 5.2 (4.7–6.4) | 5.3 (4.7–6.4) | 0.738 |
| PBG (mmol/L) | 7.5 (5.9–10.6) | 8.4 (6.4–12.9) | 8.7 (6.5–11.7) | 0.050 |
| HbA1c (%) | 5.9 (5.6–6.6) | 6.1 (5.7–6.9) | 6.2 (5.7–7.6)* | 0.019 |
| TC (mmol/L) | 4.0 (3.3–4.7) | 4.1 (3.5–4.8) | 4.0 (3.4–4.7) | 0.624 |
| TG (mmol/L) | 1.4 (1.1–2.1) | 1.4 (1.0–1.9) | 1.5 (1.1–2.0) | 0.819 |
| HDL-C (mmol/L) | 1.0 (0.9–1.2) | 1.1 (0.9–1.2) | 0.9 (0.8–1.1)*# | 0.000 |
| LDL-C (mmol/L) | 2.3 (1.7–2.9) | 2.4 (1.8–3.1) | 2.4 (1.8–3.0) | 0.830 |
| Creatinine (umol/L) | 78.0 (68.0–86.8) | 79.0 (71.0–89.0) | 82.0 (71.0–93.0)* | 0.042 |
| eGFR | 89.1 (79.0–95.6) | 86.1 (72.1–93.8) | 83.1 (71.7–95.2) | 0.065 |
| NHR | 3.4 (2.7–4.2) | 3.7 (2.6–5.0) | 4.2 (3.3–6.0)*# | 0.000 |
| LDL-C/HDL-C | 2.2 (1.7–2.9) | 2.4 (1.7–3.1) | 2.5 (1.9–3.2) | 0.090 |
| Medications | ||||
| Aspirin (%) | 157 (87.2%) | 138 (92.6%) | 149 (91.4%) | 0.215 |
| Statins (%) | 168 (93.3%) | 144 (96.6%) | 151 (92.6%) | 0.278 |
| Hypoglycemic drugs (%) | 37 (20.6%) | 32 (21.5%) | 42 (25.8%) | 0.479 |
Data were expressed as mean ± standard deviation for normally distributed continuous variables, median (interquartile range) for abnormally distributed variables and number (%) for category variables. ANOVA or Kruskal–Wallis (KW) test was performed among groups for continuous variables and Chi–square test was used for categorical variables.
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell; CRP, C reactive protein; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; eGFR, estimated Glomerular Filtration Rate; FBG, fasting blood glucose; PBG, postprandial blood glucose; HbA1c, hemoglobin A1c.
Statin includes rosuvastatin, simvastatin, pravastatin, etc. Hypoglycemic drugs include metformin, sulfonylureas, glucosidase inhibitors, glinides. *p < 0.05 vs. tertile 1; #p < 0.05 vs. tertile 2.