TABLE 7.
Percent protein inhibition of extracts treated with dermatophytes and non-dermatophytes.
| Treated samples | MIC or FICI (μg/ml) | Concentration of protein in μg | Percent protein inhibition |
|---|---|---|---|
| Trichophyton rubrum | |||
| Z. officinale (M) | 31.25 | 63 | 6 |
| Z. officinale (M) | 31.25 | 55 | 18 |
| Z. O(M) +terbinafine | 3.9 + 0.00625 | 20 | 70 |
| Z. O (DW)+terbinafine | 3.9 + 0.00625 | 5 | 92 |
| Terbinafine | 0.005 | 11 | 83 |
| Control | -- | 67 | -- |
| Trichophyton tonsurans | |||
| A. sativum (M) | 31.25 | 45 | 41 |
| Z. officinale (M) | 31.25 | 66 | 14 |
| M. piperita (DW) | 31.25 | 47 | 38 |
| N. sativa (M) | 31.25 | 37 | 52 |
| N. sativa (DW) | 31.25 | 33 | 57 |
| L. inermis (M) | 31.25 | 41 | 47 |
| L. inermis (DW) | 31.25 | 22 | 72 |
| A. S(M)+ terbinafine | 3.9 + 0.00625 | 15 | 80 |
| Z. O(M) +terbinafine | 3.9 + 0.00625 | 22 | 71 |
| M. P (DW)+terbinafine | 3.9 + 0.00625 | 33 | 57 |
| N. S (M) +terbinafine | 3.9 + 0.00625 | 24 | 69 |
| N. S (DW) +terbinafine | 3.9 + 0.00625 | 19 | 75 |
| L. I(M) +terbinafine | 3.9 + 0.00625 | 24 | 69 |
| L. I(M) +terbinafine | 3.9 + 0.00625 | 29 | 57 |
| Terbinafine | 0.005 | 13 | 83 |
| Control | -- | 77 | -- |
| Rhizopus arrhizus | |||
| N. sativa (EA) | 31.25 | 44 | 6 |
| N. sativa (DW) | 31.25 | 23 | 51 |
| L. inermis (M) | 31.25 | 39 | 17 |
| C. longa (EA) | 31.25 | 29 | 38 |
| N. S (EA)+ Amphotericin B | 3.9 + 0.4 | 31 | 34 |
| N. S (DW) +Amphotericin B | 3.9 + 0.4 | 24 | 49 |
| L. I(M) + Amphotericin B | 3.9 + 0.4 | 11 | 77 |
| C. L (EA) + Amphotericin B | 3.9 + 0.4 | 19 | 59 |
| Amphotericin B | 3.2 | 6 | 87 |
| Control | -- | 47 | -- |
| Aspergillus niger | |||
| C. longa (EA) | 31.25 | 35 | 57 |
| C. L (EA) + Amphotericin B | 3.9 + 0.4 | 29 | 64 |
| Amphotericin B | 3.2 | 15 | 81 |
| Control | -- | 81 | -- |
| Fusarium dimerum | |||
| L. inermis (M) | 31.25 | 38 | 39 |
| L.I(M) + Amphotericin B | 3.9 + 0.4 | 30 | 52 |
| Amphotericin B | 3.2 | 8 | 87 |
| Control | -- | 62 | -- |
“--", not observed; control, untreated fungal protein concentration; MIC, minimum inhibitory concentration; FICI, fractional inhibitory concentration index; A. S, Allium sativum; Z. O, Zingiber officinale; N. S, Nigella sativa; M. P, Mentha piperita; L. I, Lawsonia inermis; C. L, Curcuma longa; EA, ethyl acetate extract; DW, distilled water extract; M, methanolic extract.